Listar por autor "Bou, Germán"

Mostrando ítems 1-13 de 13

    • A New and Efficient Enrichment Method for Metagenomic Sequencing of Monkeypox Virus 

      Aja-Macaya, Pablo; Rumbo-Feal, Soraya; Poza, Margarita; Cañizares Castellanos, Angelina; Vallejo, J. A.; Bou, Germán (Springer, 2022-01-17)
      [Abstract] Background The methodology described in previous literature for Monkeypox virus (MPXV) sequencing shows low efficiency when using metagenomic approaches. The aim of the present study was to evaluate a new ...

    • Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter junii Conferred by Acquisition of blaOXA-24/40 and Genetic Characterization of the Transmission Mechanism between Acinetobacter Genomic Species 

      Lasarte-Monterrubio, Cristina; Guijarro, Paula; Bellés, Alba; Vázquez-Ucha, Juan Carlos; Arca-Suárez, Jorge; Fernández-Lozano, Carlos; Bou, Germán; Beceiro, Alejandro (American Society for Microbiology, 2022)
      [Abstract] Carbapenem resistance is increasing among Gram-negative bacteria, including the genus Acinetobacter. This study aimed to characterize, for the first time, the development of carbapenem resistance in clinical ...

    • CRISPR-Cas, a Revolution in the Treatment and Study of ESKAPE Infections: Pre-Clinical Studies 

      González de Aledo, Manuel; González-Bardanca, Mónica; Blasco, Lucía; Pacios Santamaría, Olga; Bleriot Rial, Ines; Fernández-García, Laura; Fernández-Quejo, Melisa; López, María; Bou, Germán; Tomás, María (MDPI, 2021-06-22)
      [Abstract] One of the biggest threats we face globally is the emergence of antimicrobial-resistant (AMR) bacteria, which runs in parallel with the lack in the development of new antimicrobials. Among these AMR bacteria ...

    • In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa 

      Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-06-23)
      [Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ...

    • In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii 

      Conde-Pérez, Kelly; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Ageitos, Lucía; Rumbo-Feal, Soraya; Martínez-Guitián, Marta; Trigo Tasende, Noelia; Rodríguez, Jaime; Bou, Germán; Jiménez, Carlos; Beceiro, Alejandro; Poza, Margarita (Frontiers, 2021-10-05)
      [Abstract] Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. ...

    • Involvement of HisF in the persistence of Acinetobacter baumannii during a pneumonia infection 

      Martínez-Guitián, Marta; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Conde-Pérez, Kelly; Lasarte-Monterrubio, Cristina; Vallejo, J. A.; Bou, Germán; Poza, Margarita; Beceiro, Alejandro (Frontiers, 2019)
      [Abstract] Acinetobacter baumannii is currently considered one of themost problematic nosocomial microorganisms. In the present work the hisF gene from the ATCC 17978 strain and the AbH12O-A2 clinical isolate of A. baumannii ...

    • Kpi, a Chaperone-Usher Pili System Associated with the Worldwide-Disseminated High-Risk Clone Klebsiella Pneumoniae ST-15 

      Gato, Eva; Vázquez-Ucha, Juan Carlos; Rumbo-Feal, Soraya; Álvarez-Fraga, Laura; Vallejo, J. A.; Martínez-Guitián, Marta; Beceiro, Alejandro; Ramos Vivas, Jose; Sola-Campoy, Pedro Juan; Pérez-Vázquez, María; Oteo, Jesús; Rodiño-Janeiro, Bruno Kotska; Romero, Antonio; Poza, Margarita; Bou, Germán; Pérez, Astrid (National Academy of Sciences, 2020-07-08)
      [Abstract] Control of infections caused by carbapenem-resistant Klebsiella pneumoniae continues to be challenging. The success of this pathogen is favored by its ability to acquire antimicrobial resistance and to spread ...

    • Marine Organisms from the Yucatan Peninsula (Mexico) as a Potential Natural Source of Antibacterial Compounds 

      Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Gómez, Patricia; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Novoa Olmedo, María Lourdes; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-07-18)
      [Abstract] A total of 51 sponges (Porifera) and 13 ascidians (Chordata) were collected on the coast of the Yucatan Peninsula (Mexico) and extracted with organic solvents. The resulting extracts were screened for antibacterial ...

    • Modeling the Number of People Infected With SARS-COV-2 From Wastewater Viral Load in Northwest Spain 

      Vallejo, J. A.; Trigo Tasende, Noelia; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; López-Oriona, Ángel; Barbeito, Inés; Vaamonde, Manuel; Tarrío-Saavedra, Javier; Reif López, Rubén; Ladra, Susana; Rodiño-Janeiro, Bruno Kotska; Nasser-Ali, Mohammed; Cid, Ángeles; Veiga, María Carmen; Acevedo, Antón; Lamora, Carlos; Bou, Germán; Cao, Ricardo; Poza, Margarita (Elsevier, 2022)
      [Abstract] The quantification of the SARS-CoV-2 RNA load in wastewater has emerged as a useful tool to monitor COVID–19 outbreaks in the community. This approach was implemented in the metropolitan area of A Coruña (NW ...

    • Presence of Bacterial DNA in Thrombotic Material of Patients with Myocardial Infarction 

      Piñón-Esteban, Pablo; Núñez, Lucía; Moure, Raquel; Marrón Liñares, Grecia Manuela; Flores Ríos, Xacobe; Aldama López, Guillermo; Salgado-Fernández, Jorge; Calviño-Santos, Ramón; Rebollal-Leal, Fernando; Pan Lizcano, Ricardo Francisco; Vázquez-González, Nicolás; Bou, Germán; Tomás, María; Hermida-Prieto, Manuel; Vázquez Rodríguez, José Manuel (Nature Publishing Group, 2020-10-01)
      [Abstract] Infectious agents have been suggested to be involved in etiopathogenesis of Acute Coronary Syndrome (ACS). However, the relationship between bacterial infection and acute myocardial infarction (AMI) has not yet ...

    • Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing 

      Mena, Álvaro; Moldes, Luz; Meijide, Héctor; Cañizares, Angelina; Castro-Iglesias, Ángeles; Delgado, Manuel; Pértega-Díaz, Sonia; Pedreira, José D.; Bou, Germán; Poveda, Eva (PLoS ONE, 2014-12-01)

    • Survival impact of previous statin therapy in patients hospitalized with COVID-19 

      Barge-Caballero, Eduardo; Marcos-Rodríguez, Pedro J.; Doménech, Nieves; Bou, Germán; Cid-Fernández, Javier; Iglesias Reinoso, Raquel; López Vázquez, Paula; Muñiz, Javier; Vázquez-Rodríguez, José M.; Crespo-Leiro, María Generosa (Elsevier, 2022-12-07)
      [Abstract] tIntroduction: Statin therapy might have a beneficial prognostic effect in patients with COVID-19, givenits immunomodulative, anti-inflammatory and anti-atherosclerotic properties. Our purpose was to testthis ...

    • Wastewater early warning system for SARS-CoV-2 outbreaks and variants in a Coruña, Spain 

      Trigo-Tasende, Noelia; Vallejo, Juan Andrés; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; Vaamonde, Manuel; López-Oriona, Ángel; Barbeito, Inés; Nasser-Ali, Mohammed; Reif López, Rubén; Rodiño-Janeiro, Bruno Kotska; Fernández-Álvarez, Elisa; Iglesias Corrás, Iago; Tarrío-Saavedra, Javier; Tomás, Laura; Gallego-García, Pilar; Posada, David; Bou, Germán; López-de-Ullibarri, Ignacio; Cao, Ricardo; Susana, Ladra; Poza, Margarita (Springer, 2023-07)
      [Abstract]: Wastewater-based epidemiology has been widely used as a cost-effective method for tracking the COVID-19 pandemic at the community level. Here we describe COVIDBENS, a wastewater surveillance program running ...